These two sides met in April and May and both teams scored in Estudiantes’ home fixture with them. Flamengo have seen goals at both ends in four of their last five, while the hosts have in three of their last four at home.

Eintracht Frankfurt have been involved in a string of crazy contests this season and their five Bundesliga matches have finished with score lines of 6-0, 4-1, 3-3, 3-1 and 2-2. Both sides have scored in all six of Cologne’s games this term and over 3.5 rates a play.

Horsens’ Superliga games this term have averaged 3.7 goals per game and over 2.5 goals has been a winner in eight of their last nine in all competitions. Rangers have seen three or more goals scored in their last three away games, including a six-goal thriller at Sonderjyske in their last away day.

Heerenveen have only won one of their last seven games and haven’t won at home since the opening weekend of the Eredivisie season, while Excelsior are yet to lose after four away games this season, including a 2-2 draw with Ajax before the international break.

Horsens’ Superliga games this term have averaged 3.7 goals per game and over 2.5 goals has been a winner in eight of their last nine in all competitions. Rangers have seen three or more goals scored in their last three away games, including a six-goal thriller at Sonderjyske in their last away day.

Reims may be unbeaten this season, but they have drawn five of their eight games and have only picked up one win in four home fixtures. Dijon are on a four-game unbeaten streak and haven’t lost any of their four trips away this season.

Deportivo La Coruna have seen both teams score in seven of their eight La Liga matches and they face a Levante side that have scored six and conceded ten in their last three games, with goals at both ends in each of them.

Cologne have lost their last two Bundesliga away games but have found the net in both of them. They should be good for a goal, but Eintracht Frankfurt have the quality to take all three points on Friday.

Sassuolo put in a solid performance to hold Milan to a 1-1 draw at the Stadio Citta del Tricolore and they can follow up that good effort by winning on the road at Frosinone.

Burnley may be having a miserable season, but they have lost just one of their six home games and face a Wolves side that have lost three of their last four games. The visitors only have one win in their last five on the road and look set for more disappointment.

Horsens’ Superliga games this term have averaged 3.7 goals per game and over 2.5 goals has been a winner in eight of their last nine in all competitions. Rangers have seen three or more goals scored in their last three away games, including a six-goal thriller at Sonderjyske in their last away day.

Reims may be unbeaten this season, but they have drawn five of their eight games and have only picked up one win in four home fixtures. Dijon are on a four-game unbeaten streak and haven’t lost any of their four trips away this season.

Heerenveen have only won one of their last seven games and haven’t won at home since the opening weekend of the Eredivisie season, while Excelsior are yet to lose after four away games this season, including a 2-2 draw with Ajax before the international break.

Deportivo La Coruna have seen both teams score in seven of their eight La Liga matches and they face a Levante side that have scored six and conceded ten in their last three games, with goals at both ends in each of them.

Both teams have scored in all three of Clermont’s Ligue 1 away games this season and in three of their last four overall, while Laval have seen goals at both ends in each of their last four league fixtures.

Reims may be unbeaten this season, but they have drawn five of their eight games and have only picked up one win in four home fixtures. Dijon are on a four-game unbeaten streak and haven’t lost any of their four trips away this season.

Burnley may be having a miserable season, but they have lost just one of their six home games and face a Wolves side that have lost three of their last four games. The visitors only have one win in their last five on the road and look set for more disappointment.

Shamrock Rovers may be top of the Irish Premier Division, but they have only the fourth best away record and head to Galway winless in their last eight competitive trips away. Friday’s hosts have avoided defeat in eight of their last ten home games.

Heerenveen have only won one of their last seven games and haven’t won at home since the opening weekend of the Eredivisie season, while Excelsior are yet to lose after four away games this season, including a 2-2 draw with Ajax before the international break.

Cologne have lost their last two Bundesliga away games but have found the net in both of them. They should be good for a goal, but Eintracht Frankfurt have the quality to take all three points on Friday.

Five of Burnley’s six home games have ended as score draws and three of these have been 1-1 affairs, while Wolves have scored three and conceded five across their last five matches.

Four of Dedportivo La Coruna’s eight matches this season have ended as a score draw and three of those have been 1-1, while three of Levante’s eight assignments have also ended all square.

Monaco have spent the last couple of seasons in the Champions League, losing 5-4 on aggregate to PSG in last season’s knockouts.

They’ve appointed former Flamengo boss Filipe Luiz as their new manager, and the former Chelsea defender has an impressive track record. He led the Brazilian side to their domestic title, and brought continental success in the Copa Libertadores.

Strasbourg reached the last four of the Conference League last term, and this Monaco side are capable of going even further under a highly-rated young manager.

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City aren’t quite right yet under Enzo Maresca. They may well come good but Lens away was arguably the worst road trip from Pot 4 while Napoli and Leipzig represent stern tests from Pot 3. And then there’s PSG and Barcelona. Altogether a tough test.

The home game against Bodo/Glimt and trip to Slavia ought to be the bedrock of a campaign in which Dino Toppmoller’s impressive group – who have already beaten PSG in the French Champions Trophy – can emerge successfully.

Barcelona could easily lose in Paris, legitimately drop points at Galatasaray and at home to Man City. One more slip and the top eight could feasibly elude them.

Arsenal were flawless 12 months ago and should have no difficulty getting to the 16 points which are probably required.

BVB came close to the top eight last season and have a great draw this year with Betis, AEK Athens, Sabah and even Inter Milan at home looks winnable.

PSV’s hammerings of Napoli and Liverpool last term were rare highs in an otherwise disappointing campaign. This season’s draw looks far kindlier for Peter Bosz and his Eredivisie big-hitters.