The Minnesota Vikings have leaned on an elite defence to reach 5-0 but their offensive output remains underwhelming and they look unlikely to blow away the Indianapolis Colts. Indy fired GM Chris Ballard earlier this week and that could spark an improvement from Daniel Jones and his teammates.

Houston Texans are asked to cover a big number a week after victory in London and a win by double digits could prove beyond them. The Giants, who are set to start JJ McCarthy at quarterback, have had an up-and-down season but they’ve suffered just two losses and only one by more than ten points.

The 49ers are beginning to look like the best team in the NFL this season and they should be able to boost their 6-0 record by claiming another win in Atlanta. Their opponents have already fallen to defeats in all three of their games in their home stadium this season and look vulnerable.

Tampa Bay will have Baker Mayfield back, but he may need some time to adjust. Even with their starting QB in the side, this one might be beyond Tampa Bay. Carolina have put up 37 and 32 points in two home games this season and the Bucs appear unable to match their offensive output.

Houston Texans are asked to cover a big number a week after victory in London and a win by double digits could prove beyond them. The Giants, who are set to start JJ McCarthy at quarterback, have had an up-and-down season but they’ve suffered just two losses and only one by more than ten points.

The 49ers are beginning to look like the best team in the NFL this season and they should be able to boost their 6-0 record by claiming another win in Atlanta. Their opponents have already fallen to defeats in all three of their games in their home stadium this season and look vulnerable.

Tampa Bay will have Baker Mayfield back, but he may need some time to adjust. Even with their starting QB in the side, this one might be beyond Tampa Bay. Carolina have put up 37 and 32 points in two home games this season and the Bucs appear unable to match their offensive output.

The Lions have won 14 of their last 20 games when a home favourite, but Packers quarterback Jordan Love looks to have their number. He threw six touchdowns and no interceptions in their two meetings last year and he can repeat the trick on Sunday to get Green Bay over the line.

The Rams were highly fancied for Super Bowl glory this year but three defeats in their last four games have left them struggling. The Raiders have lost their last three games but fell to three-point defeats against Buffalo and Kansas City, so they should be able to keep this one competitive.

The undefeated Chiefs are underdogs for their Sunday night trip to Seattle, but they can cover despite the Seahawks’ defensive strengths. New running back Kenneth Walker can play a starring role against his former team while they have the best quarterback in Patrick Mahomes.

The Lions have won 14 of their last 20 games when a home favourite, but Packers quarterback Jordan Love looks to have their number. He threw six touchdowns and no interceptions in their two meetings last year and he can repeat the trick on Sunday to get Green Bay over the line.

The Rams were highly fancied for Super Bowl glory this year but three defeats in their last four games have left them struggling. The Raiders have lost their last three games but fell to three-point defeats against Buffalo and Kansas City, so they should be able to keep this one competitive.

The undefeated Chiefs are underdogs for their Sunday night trip to Seattle, but they can cover despite the Seahawks’ defensive strengths. New running back Kenneth Walker can play a starring role against his former team while they have the best quarterback in Patrick Mahomes.